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NAD+ Therapy and Age-Related Degenerative Disorders

A whole cascade of events goes into the aging process. Cells start to reproduce with less fidelity, and the telomerase on DNA tends to erode, leaving DNA open to more mutations. Some of this is just the cycle of life, but some of these changes are accelerated by stressors and toxins in our environment. Increasingly, NAD+ infusion is considered a viable solution for optimizing cellular health and slowing the aging process.

Administered intravenously, NAD+ is quickly becoming a new way to treat many age-related diseases and disorders, as well as improve the overall health of the people using it. NAD+ is vital for creating energy in the body and regulating cellular processes — two crucial factors in slowing aging and age-related degenerative disorders, and improving internal bodily functions.

This article from Mindful Infusions of TN will dive into what NAD+ is, how it works, and the benefits it has to offer.

What Is NAD+?

NAD+ is the acronym for nicotinamide adenine dinucleotide. It is a vital molecule for the health and well-being of all life on earth — from bacteria and yeast to plants and human beings.

NAD+ plays a primary role in the function of the mitochondria, which supply energy to the body on a cellular level. NAD+ converts food into energy and, most importantly, maintains DNA integrity and proper cell function to protect our bodies from disease and aging.

NAD+ is made of two parts, called nucleotides: an adenine nucleobase and nicotinamide. These two nucleotides are joined through phosphate bonds. NAD+ is a factor in hundreds of metabolic processes, from mitochondrial energy to cellular health. Also, since NAD+ is a coenzyme (organic compounds required by many enzymes for catalytic activity) to vitamin B3, it is a factor in more reactions in the body than any other vitamin-derived molecule.

How Does NAD+ Work?

NAD+ works as a shuttle for transporting electrons throughout the body to carry out multiple reactions and processes vital to the survival of our bodies. When it interacts with a similar molecule, NADH, the reaction produces energy in our cells. Basically, without NAD+, we would not have enough energy to survive.

There are three processes by which our bodies make NAD+:

  1. The Kynurenine (de novo) Pathway: Involves converting tryptophan (yes, the one associated with turkey) into NAD+ in the aqueous parts of cells (cytosol).
  2. The Preiss-Handler Pathway: This pathway involves the nicotinic acid found in food or dietary supplements. Nicotinic acid is a precursor molecule produced by bacteria in the intestines and saliva. It converts to NAD+ in three steps involving various nicotinic enzymes. 
  3. The Salvage Pathway: Uses a naturally occurring compound related to vitamin B3. The compounds nicotinamide, nicotinic acid, nicotinamide mononucleotide (NMN), and nicotinamide riboside (NR) are converted to NAD+ using various enzymes.

NAD+ and Aging

Unfortunately, the human body does not have an endless supply of NAD+. As we age, NAD+ production in the body declines, resulting in physical aging characteristics (such as looser skin and wrinkles) and age-related degenerative disorders, such as:

  • Parkinson’s disease
  • Alzheimer’s disease
  • Depression
  • Risk of falls and lack of endurance/energy
  • Muscle weakness and gait changes
  • Sensory changes (vision, hearing, and smell)

However, recent studies have shown that raising intracellular NAD+ levels can be a way to prevent age-associated degenerative diseases and extend one’s lifespan.

NAD+ therapy is known to slow down the aging process and can help you look and feel more youthful. At Mindful Infusions of TN, our patients say they feel refreshed, younger, and more energetic after an NAD+ therapy session. Click the link below to learn more about Mindful Infusions of TN and how NAD+ therapy can help improve your life.

What Are the Benefits of NAD+?

NAD+ research is discovering many health and aging-reversal factors that can benefit humans looking to slow down the aging process and maintain or improve their health.

Here are some of the benefits patients have reported after NAD+ therapy:

  • Reversal and protection against aging
  • Protecting and repairing DNA
  • Improving neurodegenerative diseases
  • Regulating one’s sleep cycle
  • Increasing cellular communication
  • Improving focus and memory
  • Strengthening the immune system
  • Reversing insulin resistance
  • Improving metabolism

What Is the Future of NAD+?

NAD+ was discovered in 1906 by two chemists trying to understand fermentation better. More than 100 years later, scientists are only beginning to discover the health and anti-aging benefits associated with NAD+.

The discovery of coenzymes has led scientists to believe there is excellent potential for NAD+, resulting in exciting new research for its uses.

While most testing is still underway in animals, Elysium, a company that translates scientific advancements in aging research into accessible health products and technologies, conducted a human study in 2017. It found that daily doses of an NAD+ precursor increased NAD+ levels by 40%.

While NAD+ has not been proven to reverse aging yet, studies show that it can at least slow down the aging process and inhibit the onset of age-related degenerative disorders.

What Is NAD+ Therapy?

During NAD+ therapy, a high dose of NAD+ is injected into the bloodstream via intravenous (IV) infusion. Injection ensures maximum absorption into the body by bypassing the digestive system. NAD+ therapy will activate and increase the level of your present NAD+, giving you an immediate energy boost.

NAD+ therapy has been shown to repair the body’s cells, including brain neurons, allow your cells to produce more energy, and optimize cellular functions. Patients involved in NAD+ therapy have often reported immediate results of:

  • Increased energy
  • Mood improvement
  • Increased focus and concentration
  • Improved memory
  • Higher mental clarity
  • Sight and hearing improvement
  • Decreased pain and withdrawal symptoms

While further testing is still being done, signs point to the fact that by adding NAD+ therapy to your life, you may be able to slow the effects of aging and age-related degenerative disorders. NAD+ therapy is a low-toxicity, highly effective way to a longer and healthier life.

Final Thoughts

Research for NAD+ therapy is progressing quickly, and we are beginning to see how it could improve the lives of so many people. Initial research points to NAD+ as an effective way to slow down the aging process and prevent the onset of age-related degenerative disorders.

Mindful Infusions of Tennessee is a patient-centered, evidence-based medical practice specializing in outpatient ketamine, NAD+, and vitamin infusions. We are a concierge-minded practice in terms of accessibility and convenience. With us, it’s more about the patient experience. We aim to restore your well-being in a peaceful environment conducive to healing and promoting wellness. Contact us today!

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